Death's Game centers on Choi Yee-jae, a young man who attempts suicide after struggling to find a job for seven years. Death, however, is offended by Yee-jae's lack of concern for dying and chooses to punish him by making him play a game in which he must reincarnate and die 12 times before being sent to hell. But Yee-jae discovers that if he survives in any of the 12 incarnations, he will be able to continue living. Even after taking his own life, he begins to question whether things would have gone differently if he had lived the lives of others.