Ye Feng gained immortality a thousand years ago in Kunlun Mountain to save his beloved, founding the Heavenly Dao Medical Sect but growing detached. His apprentice arranged a marriage with doctor Qin Wei to break his emotional ties, but she publicly rejected him. Later, he met Su Qingwan, who looked identical to his lost love, and married into her family amid ridicule. Ye helped the Su family win business bids, triggering jealousy and false drug accusations. He defeated Qin Wei who joined rival medical association in a medical contest, saved Chinese medicine from foreign challenges, and revealed his true identity. On his wedding night, he and Su returned to Kunlun, discovering he had died long ago and was kept alive by a fairy to protect Su's reincarnation. After his soul faded, Su sacrificed her life force to return to the past and protect young Ye Feng.